Brexit could leave Britain short of 51,000 nurses - enough to staff 45 hospitals.
Fresh concerns have been raised over a nursing shortfall post-Brexit according to a review.
Eurasia Diary reports citing to Mirrors, in England, the latest nursing vacancy rate figure is 41,722.
But analysis shows this could rise by 10,000 after we leave the EU meaning an overall shortfall of more than 51,000.
The authors of the report from the National Institute of Economic and Social Research, explored the trends in the health and social care sector's workforce, including the role of European nationals working for the NHS.
It estimates that in the short run, the UK may have an additional shortage of around 2,700 nurses.
And projecting this shortfall over the remaining period of Brexit transition to 2021, there maybe a shortfall of 5,000 to 10,000 nurses.
There are also concerns about the immigration system for EU nationals after we leave.
At the moment many social care and health jobs do not fulfil the requirements for the minimum skills or salary levels of the current system for wokers from outside the EU.
The report, which was commissioned by the Cavendish Coalition of 36 health and care charities, also warns that waiting times for patients are increasing in NHS Trusts which are losing more European workers, particularly nurses.
The Royal College of Nursing has repeatedly warned that Brexit is likely to exacerbate the nursing shortfall.
In the 12 months since the referendum, before the UK has formally left the bloc, the number of EEA nurse joiners to the NHS in England fell by 17.6% while the number of leavers rose by 15.3%.
"These startling figures should be taken extremely seriously by those negotiating our departure from the EU," said Danny Mortimer, co-convenor of the coalition and chief executive of the NHS Employers organisation.
"The health and social care sector is deeply reliant on talented colleagues from across Europe and the rest of the world so it is deeply disheartening to see these projected workforce gaps at a time of rising demand for services."
The government has said that all EU nationals in the UK before the leave date of 29 March 2019 will have a right to stay.
Those that have been here for five years can apply for 'settled status' meaning they can stay here indefinitely.
But so far around 1,000 people – just 0.03% of the total number of EU citizens in the UK – have been granted settled status.
The report calls for the Home Office to guarantee that its settled status programme for EU nationals will be honoured in the event of a no-deal Brexit.
A Department of Health and Social Care spokesman said: "We greatly value the contribution of nurses to the NHS and we hope those from the EU will take up the early opportunity to secure their future in the UK.
"There are 11,900 more nurses on our wards since 2010, 52,000 nurses currently in NHS training and we have made more funding available to increase university training places."
"Later this year, we will also set out plans to reform the adult social care system to make it sustainable for the future, including how better to attract and retain staff."
