Muscle loss in old age linked to fewer nerve signals

Health 22:07 12.03.2018
Researchers say they may have worked out why there is a natural loss of muscle in the legs as people age - and that it is due to a loss of nerves.
 
In tests on 168 men, they found that nerves controlling the legs decreased by around 30% by the age of 75.
 
This made muscles waste away, but in older fitter athletes there was a better chance of them being 'rescued' by nerves re-connecting.
 
The scientists published their research in the Journal of Physiology.
 
As people get older, their leg muscles become smaller and weaker, leading to problems with everyday movements such as walking up stairs or getting out of a chair.
 
It is something that affects everyone eventually, but why it happens is not fully understood.
 
Prof Jamie McPhee, from Manchester Metropolitan University, said young adults usually had 60-70,000 nerves controlling movement in the legs from the lumbar spine.
 
But his research showed this changed significantly in old age.
 
"There was a dramatic loss of nerves controlling the muscles - a 30-60% loss - which means they waste away," he said.
 
"The muscles need to receive a proper signal from the nervous system to tell them to contract, so we can move around."
 
The research team from Manchester Metropolitan University worked with researchers from the University of Waterloo, Ontario, and the University of Manchester.
 
They looked at muscle tissue in detail using magnetic resonance imaging (MRI) and they recorded the electrical activity passing through the muscle to estimate the numbers and the size of surviving nerves.
 
The good news is that healthy muscles have a form of protection: surviving nerves can send out new branches to rescue muscles and stop them wasting away.
 
This is more likely to happen in fit people with large, healthy muscles, Prof McPhee said.
 
Although it is not known why connections between muscles and nerves break down with age, finding out more about muscle loss could help scientists find ways of reversing the condition in the future.
Hearings on the "Armenia v. Azerbaijan" case continue at the Hague Court - LIVE

News line

Paris 2024 torch lit in ancient Olympia, relay under way
Paris 2024 torch lit in ancient Olympia, relay under way
16:19 16.04.2024
Azerbaijan to relocate 156 more families to city of Fuzuli
16:07 16.04.2024
The Agenda to Destabilize the South Caucasus - OPINION
15:25 16.04.2024
Zelenskyy says Ukraine ready to negotiate with Russia
15:13 16.04.2024
US Department of Defense Confirms Intercept of 87 UAVs in Iran's Attack on Israel
15:00 16.04.2024
Major infrastructure projects facing the government in the coming years disclosed
Major infrastructure projects facing the government in the coming years disclosed
14:50 16.04.2024
Azerbaijani President: ‘Efficient utilization of water resources is our primary task’
Azerbaijani President: ‘Efficient utilization of water resources is our primary task’
14:40 16.04.2024
President: After the Shirvan irrigation canal has been put into operation, Lake Hajigabul will also be filled
14:28 16.04.2024
President Ilham Aliyev: Caspian Sea water desalination project is underway
14:12 16.04.2024
Ilham Aliyev: 'Unmatched Scale of Work is being implemented in Karabakh and Eastern Zangazur'
14:03 16.04.2024
Azerbaijan weather forecast for April 17
Azerbaijan weather forecast for April 17
14:00 16.04.2024
Official Tehran reveals the weapons that will be used in the 2nd stage of response against Israel
13:50 16.04.2024
China Leads Global Nuclear Expansion with 26 Reactors Under Construction
China Leads Global Nuclear Expansion with 26 Reactors Under Construction
13:40 16.04.2024
Media: Israel has a secret plan against Iran
13:25 16.04.2024
Energy Concerns for World: Europe and North America's Undersea Communication Networks at Risk
Energy Concerns for World: Europe and North America's Undersea Communication Networks at Risk
13:05 16.04.2024
The real face of Nobel Prize nominee Vardanyan... - "Money Laundering" reports
12:50 16.04.2024
Azerbaijan extends period of providing supplements to salaries of health workers fighting COVID-19
Azerbaijan extends period of providing supplements to salaries of health workers fighting COVID-19
12:35 16.04.2024
Population Decline Continues in Japan: Largest Decrease Since 1950
12:25 16.04.2024
Hearings on the "Armenia v. Azerbaijan" case continue at the Hague Court - LIVE
12:20 16.04.2024
Borrell: EU knew in advance about Iran’s retaliatory strike on Israel
12:14 16.04.2024
Uranium Found in Soldier's Room at Holsworthy Barracks in Sydney
Uranium Found in Soldier's Room at Holsworthy Barracks in Sydney
12:00 16.04.2024
Female Demining Teams Trained at Tartar Regional Vocational Training Center of IEPF - PHOTOS
11:49 16.04.2024
Will US impose oil sanctions on Iran?
11:40 16.04.2024
EU Ambassador Vasilis Maragos Urges Recognition of Former Soviet Administrative Borders as International
11:28 16.04.2024
Leaders meeting: EU Actively Engaged in Peace Process Between Armenia and Azerbaijan
11:16 16.04.2024
Iran and Russia Sign Agreement for Rasht-Astara Railway Construction
11:01 16.04.2024
Azerbaijani President lays foundation stone for Shirvan irrigation canal
10:49 16.04.2024
Parliament of Georgia introduces special security regime
Parliament of Georgia introduces special security regime
10:35 16.04.2024
Landmines found in liberated Jabrayil
10:00 16.04.2024
Tunisia vows to strengthen ties with NATO
Tunisia vows to strengthen ties with NATO
09:47 16.04.2024
Expert Analysis: Israel's Defense Triumphs amidst Escalating Iran-Israel Tensions
09:30 16.04.2024
Volume of frozen Russian assets in Germany reaches around €3.9 bln
Volume of frozen Russian assets in Germany reaches around €3.9 bln
09:13 16.04.2024
Netanyahu a threat for Israel, opposition leader says
08:55 16.04.2024
The President of Georgia voiced solidarity with demonstrators in Tbilisi
The President of Georgia voiced solidarity with demonstrators in Tbilisi
23:55 15.04.2024
Saudi Arabia's involvement in preventing Iran's attacks on Israel has been denied
23:21 15.04.2024
Israel Army Chief tells soldiers Iran attack 'will be met with response'
22:26 15.04.2024
Italy closes its consulate in Tehran
Italy closes its consulate in Tehran
21:28 15.04.2024
Israel is reportedly delaying its ground operation in Rafah
21:09 15.04.2024
Delegation of the Political and Security Committee of the EU visited Aghdam - VIDEO/ PHOTOS
20:32 15.04.2024
Baku Steel Company represents Azerbaijan in Dusseldorf
Baku Steel Company represents Azerbaijan in Dusseldorf
20:00 15.04.2024
Hamısı