The UK's new prime minister made sweeping changes at the top of government on Wednesday, filling key posts with supporters who campaigned for him to take over the top role, Deutsche Welle reports.

Boris Johnson's new Cabinet had a strongly pro-Brexit flavor, with the major cabinet posts going to those who have backed his plan to take Britain out of the European Union by October 31 with or without a withdrawal deal.

Former Brexit chief negotiator Dominic Raab, who resigned from Theresa May's government in opposition to the divorce agreement struck with Brussels, was given the role of Foreign Secretary.

Raab takes over from Jeremy Hunt, who was Johnson's opponent in the final round of the race to lead Britain's ruling Conservative Party.

Raab, who was initially among the contenders to replace Theresa May, also takes on the mantle of First Secretary of State, meaning he will deputize for Johnson when the prime minister is absent.

Read more:

Priti Patel, an arch-Brexiter and former international development minister, returns to government as Home Secretary — the title given to the UK's interior minister. Patel, who was fired by May for having secret meetings with the Israeli government, was a staunch opponent of the former prime minister's withdrawal deal.

Patel takes over the role from Sajid Javid, who moves into another of the UK's Great Offices of State. Javid, a former investment banker, takes on the mantle of Chancellor of the Exchequer.

That role, the UK's finance minister, was vacated by Philip Hammond who said he would not countenance working with Johnson.

May's Justice Secretary David Gauke, International Development Secretary Rory Stewart and May's de-facto deputy, David Lidington, also resigned after Johnson took charge. Gauke and Stewart both said they would rather leave than sanction a no-deal scenario, while Lidington said it was "the right time to go."

Prominent members of the "Back Boris" leadership campaign Liz Truss and Gavin Williamson both returned to government, with the portfolios for trade and education respectively.

Health Secretary Matt Hancock and Work and Pensions Secretary Amber Rudd were among the few ministers who backed Remain — to stay in the EU — in the 2016 referendum who have kept their jobs.