Senator Elizabeth Warren has ended her presidential campaign following disappointing Super Tuesday results, EDNews reports citing BBC.
A favourite of the liberal left, the Massachusetts senator, 70, was once a front-runner in the Democratic field.
Ms Warren said she needed some time to decide on another candidate to support.
The Democratic contest to take on President Donald Trump in November is now seen as a two-horse race between former Vice-President Joe Biden, 77, and Vermont Senator Bernie Sanders, 78.
Despite early momentum for her campaign, she failed to win a single state in the first primary contests of 2020, even her own.
With Ms Warren's departure, a Democratic race that began with a record high of female candidates is now effectively left to two male front-runners, who both swiftly praised her and her campaign.
"One of the hardest parts of this is all those little girls who are going to have to wait four more years," she said alongside her husband outside her home in Cambridge, Massachusetts, on Thursday.
"That's going to be hard."