Limiting mealtimes may increase your motivation for exercise

Health 16:17 20.10.2019
Limiting access to food in mice increases levels of the hormone, ghrelin, which may also increase motivation to exercise, according to a study published in the Journal of Endocrinology. The study suggests that a surge in levels of appetite-promoting hormone, ghrelin, after a period of fasting prompted mice to initiate voluntary exercise. These novel findings indicate that better diet control, for example limiting food intake to mealtimes or fasting intermittently, could help overweight people maintain a more effective exercise routine, lose weight and avoid debilitating complications such as diabetes and heart disease.
 
Obesity is a costly and growing, global health epidemic that needs more effective intervention strategies to avoid serious complications including heart disease and diabetes. Food restriction and regular exercise are the two main cost-effective strategies to prevent and treat obesity; however the condition is often associated with a sedentary lifestyle and bad eating habits, such as snacking and binge eating. Consequently, adhering to a regular exercise regime can be difficult due to an inability to exercise for a prolonged period or a lack of motivation. Ghrelin, often referred to as the 'hunger hormone', stimulates appetite through actions on the brain reward circuitry that increase motivation to eat. It has also been reported to be essential for endurance exercise by increasing metabolism to meet the energy demands of prolonged exercise. Although previous studies have suggested a relationship between ghrelin and exercise, it is not known whether ghrelin levels have a direct effect on motivation to exercise.
 
In this study, Dr Yuji Tajiri and colleagues from Kurume University School of Medicine in Japan, investigated the relationship between exercise and ghrelin levels in mice. Food intake and wheel-running activity were compared in mice given free access to food and those fed only twice a day for a limited time. Although both groups ate a similar amount of food, the restricted mice ran significantly more. Mice genetically altered to have no ghrelin and on the restricted feeding diet ran less than the mice given free access, however, this could be reversed by administering ghrelin. Furthermore, mice given free access to food and given ghrelin also ran significantly more. These findings suggest that ghrelin may play an important role in the motivation for both feeding and exercise, in response to restricted eating plans.
 
Dr Tajiri comments, "Our findings suggest that hunger, which promotes ghrelin production, may also be involved in increasing motivation for voluntary exercise, when feeding is limited. Therefore, maintaining a healthy eating routine, with regular mealtimes or fasting, could also encourage motivation for exercise in overweight people."
 
However, Dr Tajiri cautions. "These findings and previous reports are based on animal studies; so much more work is needed to confirm that this ghrelin response is also present in people. If it can be established in clinical practice, it not only opens up new cost-effective diet and exercise strategies but may also indicate a new therapeutic application for ghrelin-mimicking drugs."
 
Dr Tajiri and his team now plan to carry out more experiments to confirm these findings in humans, to further characterise how ghrelin acts in the brain to produce motivation to eat or exercise and to explore any potential real-world, clinical benefits for the treatment and prevention of obesity.
 
Date:
October 19, 2019
Source:
Society for Endocrinology
Summary:
Limiting access to food in mice increases levels of the hormone, ghrelin, which may also increase motivation to exercise, according to a new study. The study suggests that a surge in levels of appetite-promoting hormone, ghrelin, after a period of fasting prompted mice to initiate voluntary exercise.

 

Azerbaijan Defense Minister informs NATO chief on situation in Azerbaijan-Armenia conditional border -VIDEO

News line

Pakistan restricts foreign travels of ministers, government officials
Pakistan restricts foreign travels of ministers, government officials
20:39 18.03.2024
EU to boost military support fund for Ukraine by EUR 5 bln — Hungarian foreign minister
20:00 18.03.2024
Industrial zones to be created in Azerbaijan’s Zangilan, Jabrayil, and Gubadli
19:16 18.03.2024
Reuters: Only an oil slump can stop Russia
19:00 18.03.2024
Top Hamas operative killed in hospital raid, IDF says
Top Hamas operative killed in hospital raid, IDF says
18:33 18.03.2024
President Ilham Aliyev congratulates people of Azerbaijan on occasion of Novruz holiday - UPDATED
18:00 18.03.2024
Jens Stoltenberg: We fully support Georgia's sovereignty and territorial integrity
Jens Stoltenberg: We fully support Georgia's sovereignty and territorial integrity
17:47 18.03.2024
2 dead, 6 injured in Türkiye factory explosion
2 dead, 6 injured in Türkiye factory explosion
17:28 18.03.2024
Armenia’s anti-Russian policy reaches new level
17:11 18.03.2024
"The Middle Corridor plays a key role for Green Energy" - Expert Ali Pasha
16:45 18.03.2024
Central square of Khankandi named “Victory Square”
16:22 18.03.2024
President: We demonstrated tremendous heroism during the II Karabakh War and the anti-terror operation
16:16 18.03.2024
Nobel Peace Prize Laureate Muhammad Yunus visited IEPF - PHOTOS - VIDEO
16:00 18.03.2024
Historic opportunity emerged to advance the Azerbaijani-Armenian peace agenda - FM Bayramov
15:21 18.03.2024
Bayramov and Stoltenberg discuss normalization process between Azerbaijan and Armenia
15:03 18.03.2024
Azerbaijan Defense Minister informs NATO chief on situation in Azerbaijan-Armenia conditional border -VIDEO
14:58 18.03.2024
Stoltenberg's visit to the Caucasus: "NATO is in panic" - OPİNİON
14:29 18.03.2024
Hikmat Hajiyev holds discussions for upcoming COP29 with Chinese Vice FM
Hikmat Hajiyev holds discussions for upcoming COP29 with Chinese Vice FM
14:00 18.03.2024
Stoltenberg concludes his official visit to Azerbaijan
13:42 18.03.2024
Geomagnetic storm expected on March 20
13:33 18.03.2024
Mbappe celebrates his 250th goal in PSG
Mbappe celebrates his 250th goal in PSG
13:19 18.03.2024
President Ilham Aliyev makes a phone call to Vladimir Putin
13:00 18.03.2024
President Ilham Aliyev lit Novruz bonfire in Khankandi and congratulated Azerbaijani people
12:34 18.03.2024
Foreign students attacked in India over Ramadan prayers
12:30 18.03.2024
Spring comes to Northern Hemisphere
Spring comes to Northern Hemisphere
12:17 18.03.2024
Why does Azerbaijan matter to the European Union? - OPINION
12:00 18.03.2024
Number of human remains found in mass grave in Khojaly reaches 19
11:45 18.03.2024
Hikmat Hajiyev meets Pakistani envoy to China
Hikmat Hajiyev meets Pakistani envoy to China
11:33 18.03.2024
EU Council to discuss Armenian-Azerbaijani normalization
11:23 18.03.2024
Global Terrorism Index: Azerbaijan among countries with highest anti-terror rating worldwide
10:56 18.03.2024
Oil prices keep rising
Oil prices keep rising
10:40 18.03.2024
Stoltenberg: NATO looking forward to further strengthening partnership with Azerbaijan
10:23 18.03.2024
Azerbaijani police found numerous weapons and ammunition in Khankandi
10:10 18.03.2024
President Ilham Aliyev: There is a good chance for settlement of Azerbaijan-Armenia relations
09:57 18.03.2024
Putin warns about possible war between Russia and NATO
09:40 18.03.2024
Hikmat Hajiyev meets with Vice Minister of Ecology and Environment of China
09:23 18.03.2024
Azerbaijan relocates 123 more residents to Fuzuli city
08:53 18.03.2024
President Ilham Aliyev held expanded meeting over dinner with Jens Stoltenberg
23:07 17.03.2024
Putin wins the presidential elections for fifth term, exit poll shows
22:43 17.03.2024
COP29 will be turning point, says NATO Secretary-General
21:54 17.03.2024
Hamısı