With 20 Oscar and 30 Golden Globe nominations to her names, she's been a fixture at Hollywood's award shows for decades.
So far from being impressed by the glamour of life on the red carpet, Meryl Streep treats the annual awards season as a chance to catch up with her pals.
And it was clear the 67-year-old was enjoying herself, as she called over Ryan Gosling to fix his bow tie on Sunday night at the SAG Awards.
Spotting sight of the actor, who was wearing a black suit with jauny bow tie, she immediately set to straightening him up.
Ryan laughed as he waited patiently while Meryl, who wore an embellished white long-sleeved dress, tended to him.
The two have known one another for ten years, after meeting when Ryan asked Meryl to help put his mother at ease.
Back in 2007 at the Oscars, he sat between superstar Meryl and his own mother - who had worn her hair in a beehive.
As he later recalled: 'My mom sat in front of Rachel Weisz and her hair was so high and my mom kept sinking in her chair and I didn’t know what to do ’cause I was — I wanted to have a nice night.
'I didn’t know Meryl Streep but she was sitting next to me and I said in a commercial break, "Would you mind just telling my mom you like her hair?"'
Streep didn't heistate.
'She was like, "I got this,"' Gosling recalled on the Graham Nolan show. 'And then the commercial went and she goes, "Do you know, I was gonna do a beehive and I wish I had."
'And my mom was like, raise the roof all night.
2017 SAG AWARD WINNERS
MOVIES
Outstanding Performance by a Male Actor in a Leading Role
Casey Affleck, Manchester By The Sea
Andrew Garfield, Hacksaw Ridge
Ryan Gosling, La La Land
Viggo Mortensen, Captain Fantastic
Denzel Washington, Fences - WINNER
Outstanding Performance by a Female Actor in a Leading Role
Amy Adams, Arrival
Emily Blunt, The Girl On The Train
Natalie Portman, Jackie
Emma Stone, La La Land - WINNER
Meryl Streep, Florence Foster Jenkins
Outstanding Performance by a Male Actor in a Supporting Role
Mahershala Ali, Moonlight - WINNER
Jeff Bridges, Hell or High Water
Hugh Grant, Florence Foster Jenkins
Lucas Hedges, Manchester By The Sea
Dev Patel, Lion
Outstanding Performance by a Female Actor in a Supporting Role
Viola Davis, Fences - WINNER
Naomie Harris, Moonlight
Nicole Kidman, Lion
Octavia Spencer, Hidden Figures
Michelle Williams, Manchester By The Sea
Outstanding Performance by a Cast in a Motion Picture
Captain Fantastic
Fences
Hidden Figures - WINNER
Manchester by the Sea
Moonlight
Outstanding Performance by a Stunt Ensemble in a Motion Picture
Captain America: Civil War
Dr. Strange
Hacksaw Ridge - WINNER
Jason Bourne
Nocturnal Animals
TELEVISION
Outstanding Performance by a Male Actor in a Drama Series
Sterling K. Brown, This Is Us
Peter Dinklage, Game of Thrones
John Lithgow, The Crown - WINNER
Rami Malek, Mr. Robot
Kevin Spacey, House of Cards
Outstanding Performance by a Female Actor in a Drama Series
Millie Bobby Brown, Stranger Things
Claire Foy, The Crown - WINNER
Thandie Newton, Westworld
Winona Ryder, Stranger Things
Robin Wright, House of Cards
Outstanding Performance by an Ensemble in a Drama Series
The Crown
Downton Abbey
Game of Thrones
Stranger Things - WINNER
Westworld
Outstanding Performance by a Male Actor in a Comedy Series
Anthony Anderson, Black-ish
Tituss Burgess, The Unbreakable Kimmy Schmidt
Ty Burrell, Modern Family
William H. Macy, Shameless - WINNER
Jeffrey Tambor, Transparent
Outstanding Performance by a Female Actor in a Comedy Series
Uzo Aduba, Orange Is The New Black
Jane Fonda, Grace & Frankie
Ellie Kemper, The Unbreakable Kimmy Schmidt
Julia Louis-Dreyfus, Veep - WINNER
Lily Tomlin, Grace & Frankie
Outstanding Performance by an Ensemble in a Comedy Series
The Big Bang Theory
Black-ish
Modern Family
Orange Is The New Black - WINNER
Veep
Outstanding Performance by a Male Actor in a Miniseries or Television Movie
Riz Ahmed, The Night Of
Sterling K. Brown, American Crime Story: The People V. OJ Simpson
Bryan Cranston, All The Way - WINNER
John Turturro, The Night Of
Courtney B. Vance, American Crime Story: The People V. OJ Simpson
Outstanding Performance by a Female Actor in a Miniseries or Television Movie
Bryce Dallas Howard, Black Mirror
Felicity Huffman, American Crime
Audra McDonald, Lady Day at Emerson's Bar & Grill
Sarah Paulson, American Crime Story: The People V. OJ Simpson - WINNER
Kerry Washington - Confirmation
Outstanding Performance by a Stunt Ensemble in a Television Series
Game of Thrones - WINNER
Daredevil
Luke Cage
The Walking Dead
Westworld